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Richard C. Gibbs, MD

Arch Dermatol. 1970;101(1):92-94.

Abstract
A patient is described who was shown to be allergic by closed patch testing to epinephrine-(L -epinephrine) which was contained in an ophthalmic preparation. The several other ingredients in the fluid vehicle were negative. Repeat patch testing a few months later was again positive for epinephrine, but negative for its stereoisomer D-epinephrine. Still later, further testing to epinephrine, including scratch testing, proved negative. A final episode of clinical contact dermatitis apparently caused by reexposure to the offending ophthalmic preparation was associated with negative patch-test results to epinephrine and the eye drops.

Author Affiliations
New York

From the Department of Dermatology, New York University School of Medicine, New York.

Footnotes
Accepted for publication June 25, 1969.

Reprint requests to 15 Park Ave, New York 10016.

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