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Leopoldo F. Montes, MD, CRCP(C); Annie J. Narkates, MS; Dale Hunt, PhD; Robert F. Pittillo, PhD; Ray O. Noojin, MD; Raymond J. Sherer, MD

Arch Dermatol. 1970;101(2):140-144.

Abstract
It has been suggested that bacteria and yeasts may play a role in familial benign chronic pemphigus. In an attempt to reevaluate the participation of microorganisms in this condition, bacterial and fungal cultures were performed in four patients. Coagulase-positive Staphylococcus aureus was present in the lesions. In two patients intact bullae yielded this organism in pure culture. In one patient a pure culture of S aureus was obtained from a broken bulla. Other ruptured bullae yielded S aureus in addition to members of the normal skin flora. Gram-positive cocci were localized also within bullae in sections of the skin. Phage typing showed that two of the staphylococcal isolates were lysed by phages 71, 75, and 85. Candida albicans could not be isolated from lesions of any of these patients.

Author Affiliations
Birmingham, Ala

From the departments of dermatology and microbiology, University of Alabama Medical Center, and Microbiology Division, Southern Research Institute, Birmingham, Ala.

Footnotes
Accepted for publication Sept 11, 1969.

Read before the Section of Dermatology at the 62nd annual meeting of the Southern Medical Association, New Orleans, Nov 19, 1968.

Reprint requests to the Department of Dermatology, University of Alabama Medical Center, Birmingham, Ala 35233 (Dr. Montes).

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