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Studies in Pathogenesis: Fatty Acids of Corynebacterium acnes

Robert E. Kellum, MD; Kathe Strangfeld

Arch Dermatol. 1970;101(3):337-339.

Abstract
The fatty acids from 42 isolates of Corynebacterium acnes were studied by gas-liquid chromatography, and ranged from C₁₀ to C₁₈ with trace amounts of fatty acids above C₁₈. The predominant fatty acid had a carbon number of 14.66, the relative carbon number of isobranched C₁₅ fatty acid. No significant differences were found in the fatty acid pattern of the C acnes from patients with and without acne. We believe this excludes the alternative that irritant (medium chain length, eg, C₈ to C₁₄) fatty acids are derived from C acnes.

Author Affiliations
Seattle; Portland, Ore

From the Department of Dermatology, University of Oregon Medical School, Portland. Dr. Kellum is now in private practice in Seattle.

Footnotes
Accepted for publication Nov 17, 1969.

Reprint requests to 1118 Ninth Ave, Seattle 98108 (Dr. Kellum).

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