This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (24)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

The Role of Gluten

Janet Marks, DM, MRCP; Sam Shuster, PhD, FRCP

Arch Dermatol. 1970;101(4):452-457.

Abstract
About two thirds of the patients with dermatitis herpetiformis have an enteropathy which responds to treatment with a gluten-free diet. By contrast, their rash is totally unaffected by gluten withdrawal. Likewise, the rash is unaffected by gluten withdrawal in patients with dermatitis herpetiformis who have a normal bowel. Intradermal injection of gluten does not provoke the rash.

The significance of the dose of dapsone required to control the rash is discussed. The minimal effective dose of dapsone is in most patients unaffected by gluten withdrawal.

The relationship of the enteropathy to the rash is an indirect one and patients whose enteropathy is controlled by a gluten-free diet will still need dapsone for their rash.

Author Affiliations
Newcastle upon Tyne, England

From the Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, England.

Footnotes
Accepted for publication Oct 1, 1969.

Reprint requests to the Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, England (Dr. Marks).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Dermatitis Herpetiformis and Bullous Pemphigoid: Intermediate and Mixed Forms
Jablonska et al.
Arch Dermatol 1976;112:45-48.
ABSTRACT  

Dermatitis Herpetiformis and the Enteropathy of Celiac Disease
de Launey
Arch Dermatol 1974;110:301-301.
ABSTRACT