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Childhood Bullous Dermatitis HerpetiformisNegative Immunofluorescent Tests
Robert E. Jordon, MD;
Samuel F. Bean, MD;
Clark T. Triftshauser, PhD;
Richard K. Winkelmann, MD
Arch Dermatol. 1970;101(6):629-634.
Abstract
Indirect immunofluorescent (IF) staining revealed that the sera of six patients with active childhood bullous dermatitis herpetiformis (also referred to as childhood bullous pemphigoid) were negative for basement-membrane zone or "pemphigoid" antibodies. Direct IF studies of skin lesions from three of these patients also yielded normal results, in contrast to that noted in adult bullous pemphigoid. Bullous dermatitis herpetiformis or bullous pemphigoid of childhood, therefore, appears to be immunologically distinct from bullous pemphigoid as it occurs in the adult. "Benign chronic bullous dermatosis of childhood" may be a more appropriate name for this disease.
Author Affiliations
Rochester, Minn; Minneapolis; Buffalo; Rochester, Minn
From the Mayo Graduate School of Medicine (University of Minnesota), Rochester (Dr. Jordon); Division of Dermatology, University of Minnesota, Minneapolis (Dr. Bean); Department of Microbiology, School of Medicine, State University of New York at Buffalo (Dr. Triftshauser); and Section of Dermatology, Mayo Clinic, Rochester, Minn (Dr. Winkelmann).
Footnotes
Accepted for publication Jan 31, 1970.
Reprint requests to Mayo Clinic, 200 First St SW, Rochester, Minn 55901.
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