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Unusual Cutaneous Lesions in Tumoral Calcinosis
David Ashby Whiting, MB, BCh, MMed, MRCP(Ed), DCH, DRCOG;
lan Wark Simson, MD, MRCPath;
Jeffrey Cedric Kallmeyer, MB, ChB, M Med;
Ingrid Paula Lisa Dannheimer, MB. ChB
Arch Dermatol. 1970;102(4):465-473.
Abstract
A case of tumor calcinosis with unusual cutaneous lesions occurred. The skin lesions were calcified and widespread, occurring particularly on flexural surfaces. Many of these lesions were unrelated to the large subcutaneous calcified masses, characteristic of this condition, which were situated largely over extensor or exposed surfaces. The patient was investigated extensively, and the histopathology of the dermal and subcutaneous lesions is recorded. To our knowledge no patient with similar skin lesions appears previously to have been reported. The histological appearances of these lesions lead to the suggestion that an inherited fault of collagen tissue is the primary defect in this disease.
Author Affiliations
Pretoria, South Africa
From the departments of dermatology (Dr. Whiting), pathology (Prof. Simson), and medicine (Drs. Kallmeyer and Dannheimer, University of Pretoria (South Africa), H.F. Verwoerd Hospital.
Footnotes
Accepted for publication June 27, 1970.
Reprint requests to 801 Lancet Hall, Jeppe St, Johannesburg, South Africa (Dr. Whiting).
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