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Eugene J. Van Scott, MD; Peter L. Winters, MD

Arch Dermatol. 1970;102(5):507-514.

Abstract
Complete clinical and histologic remission of plaque stage disease of mycosis fungoides was achieved in a majority of patients intensively treated with whole body applications of nitrogen mustard. Resolution of plaques and tumors was also achieved when the drug was injected intralesionally. In some patients clinical improvement was temporally associated with delayed hypersensitivity reactions to the drug. Permanence of improvement achievable by these means has not been established.

Author Affiliations
Philadelphia

From the Skin and Cancer Hospital, Department of Dermatology, Temple University Health Sciences Center, Philadelphia.

Footnotes
Accepted for publication July 21, 1970.

Read before the annual meeting of the American Dermatological Association, Boca Raton, Fla, March 21, 1970.

Reprint requests to 3322 N Broad St, Philadelphia 19140 (Dr. Van Scott).

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