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Alfred L. Weiner, MD

Arch Dermatol. 1970;102(5):540-544.

Abstract
Reactive perforating collagenosis is an apparently rare dermatologic disturbance characterized by recurrent, umbilicated, papular lesions affecting various areas of the skin and by spontaneous disappearance of the lesions in a six- to eightweek period. New lesions often appear as older ones are involuting. It appears that the disease usually affects young children. The histologic pattern of the disease is distinct and is characterized by hematoxylinophilic changes in the collagen with eventual extrusion of the abnormal material via a mechanism known as epidermal elimination. The Koebner phenomenon is regularly observed. Superficial trauma appears to be a factor in precipitation of lesions, and since the disease may occur in siblings it is thought to be one of genetic origin. There are data concerning some 11 or 12 cases of reactive perforating collagenosis; this communication concerns two additional cases.

Author Affiliations
Cincinnati

From the Department of Dermatology, University of Cincinnati College of Medicine and the University of Cincinnati Medical Center.

Footnotes
Accepted for publication July 7, 1970.

Read before the Noah Worcester Dermatological Society, Palm Springs, Calif, March 18, 1970.

Reprint requests to 2825 Burnet Ave Cincinnati 45229 (Dr. Weiner).

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