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Associated With Metastatic Skin Tumors and Cushing's Syndrome

Allan K. Izumi, MD; Stephen P. Richman, MD

Arch Dermatol. 1970;102(5):556-559.

Abstract
A case of the ectopic adrenocorticotropic hormone (ACTH) syndrome associated with malignancy and Cushing's syndrome was established by the recovery of an ACTH-like polypeptide from a metastatic cutaneous nodule. This communication emphasizes the capacity of neoplasms to produce a variety of hormone-like substances, and reviews the clinical and laboratory features of the ectopic ACTH-syndrome.

Author Affiliations
From the departments of dermatology and medicine, Hospital of the University of Pennsylvania, Philadelphia.

Footnotes
Accepted for publication July 17, 1970.

Reprint requests to Department of Dermatology, Duhring Laboratories, 3600 Spruce St, Philadelphia 19104 (Dr. Izumi).

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ABSTRACT