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Lawrence M. Solomon, MD; David Fretzin, MD; Samuel Pruzansky, DDS

Arch Dermatol. 1970;102(6):598-602.

Abstract
The clinical features of eight female patients with the oral-facial-digital (OFD) syndrome, including a description of the skin and its histological and pharmacological characteristics are described. The OFD syndrome is characterized in part by a cutaneous dyplasia which includes a marked diminution in sebaceous glands, some decrease in hair follicles, and early keratinous cyst formation, which may represent maldevelopment of the pilosebaceous unit.

Author Affiliations
Chicago

From the Department of Dermatology and Center for Cranio-facial Anomalies, colleges of medicine and dentistry, University of Illinois, Chicago.

Footnotes
Accepted for publication Aug 21, 1970.

Reprint requests to Department of Dermatology, College of Medicine, University of Illinois, 840 S Wood St, Chicago 60680 (Dr. Solomon).

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