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Complication of High Dosage Steroids in Bullous Pemphigoid

Kenneth M. Stein, MD; Carl R. Raque, MD; Dick D. Harrell, MD; M. H. Samitz, MD

Arch Dermatol. 1970;102(6):674-676.

Abstract
A patient with progressive bullous pemphigoid developed an occult lung abscess while being treated with high dosage corticosteroids. The lung abscess was successfully treated with long-term, high dosage, intravenously administered penicillin. Resistance to infection while receiving steroid therapy is discussed, and lung abscess as a complication of steroid therapy is reviewed. The insidious appearance of this unusual, but often fatal complication, in a patient with bullous pemphigoid, successfully treated, with concomitant resolution of the pemphigoid, prompted this case report.

Author Affiliations
Philadelphia

From the Department of Dermatology, University of Pennsylvania School of Medicine (Drs. Stein, Raque, and Samitz), and the Department of Medicine, Graduate Hospital (Dr. Harrell), Philadelphia.

Footnotes
Accepted for publication Aug 19, 1970.

Reprint requests to Department of Dermatology, Duhring Laboratories, Hospital of the University of Pennsylvania, Philadelphia 19104 (Dr. Samitz).

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