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Isozymes of NADP-linked Isocitric Dehydrogenase in Psoriasis and Human Basal Cell Carcinoma
Kiyomi Fukui, MD;
Kenneth M. Halprin, MD;
Akira Ohkawara, MD;
J. Richard Taylor, MD
Arch Dermatol. 1971;103(2):185-190.
Abstract
Four isozymes of nicotinamide-adenine dinucleotide phosphate (NADP) linked isocitric dehydrogenase can be demonstrated by starch gel electrophoresis in normal human epidermis. In the lesions of psoriasis and in basal cell carcinoma only two of these isozymes can be demonstrated. With healing of the psoriatic lesion the two missing isozymes return.
Author Affiliations
Miami, Fla
From the Dermatology Service, Veterans Administration Hospital, and the Department of Dermatology, University of Miami School of Medicine, Miami, Fla. Drs. Fukui and Ohkawara are now at the University of Hokkaido Medical School, Sapporo, Hokkaido, Japan.
Footnotes
Accepted for publication Oct 20, 1970.
Reprint requests to Chief of Dermatology, Veterans Administration Hospital, 1201 NW 16th St, Miami, Fla 33125 (Dr. Halprin).
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