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Cosmetic AllergyA Comprehensive Study of the Many Groups of Chemical Antimicrobial Agents
William F. Schorr, MD
Arch Dermatol. 1971;104(5):459-466.
Abstract
Antimicrobials or preservatives are used in all cosmetic emulsions as well as in dermatologic medications. Parabens, sorbic acid, phenolics, formaldehyde, organic mercurials, quaternary ammonium compounds, betaines, dimethoxane, and dehydroacetic acid represent the chemicals most often employed for this purpose. It is my purpose to present a comprehensive review of the relative sensitizing potential of each chemical, delineate their usage, and explore diagnostic techniques as well as proper substitution therapy. Attention is also called to the problems of the cosmetic chemist as well as to advantages and disadvantages of particular antimicrobial chemicals.
Author Affiliations
Marshfield, Wis
From the Department of Dermatology, Marshfield (Wis) Clinic.
Footnotes
Accepted for publication March 2, 1971.
Reprint requests to Department of Dermatology, Marshfield Clinic, 630 S Central Ave, Marshfield, Wis 54449 (Dr. Schorr).
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