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Verrucae Vulgaris RejectionA Preliminary Study of Contact Dermatitis and Cellular Immunity Response
MAJ Joseph H. Greenberg, MC;
MAJ T. Larry Smith, MC;
Roger M. Katz, MD
Arch Dermatol. 1973;107(4):580-582.
Abstract
Clinical and histologic correlations were performed on five adult patients with verrucae vulgaris lesions and on four normal adult volunteers without verrucae after induction of irritant contact dermatitis and subsequent allergic contact immune response to 1-nitro-2,4-dichlorobenzene (DNCB). Four of the five patients with warts and all of the control patients developed normal delayed cutaneous hypersensitivity (DCH) reactions. The four patients with verrucae vulgaris, with induced DCH responses, had disappearance of the warts after topical challenge by DNCB. After several weeks, two of these patients experienced complete disappearance of all nontreated warts, as well.
Author Affiliations
USA; USA; Fort Sam Houston, Tex
From the Department of Dermatology (Drs. Greenberg and Smith), and the Allergy-Immunology Service (Dr. Katz), Brooke General Hospital, Fort Sam Houston, Tex. Dr. Katz is now at UCLA School of Medicine, Los Angeles.
Footnotes
Accepted for publication Nov 21, 1972.
Reprint requests to Department of Pediatrics, Division of Allergy and Immunology, UCLA School of Medicine, Los Angeles 90024 (Dr. Katz).
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