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LTC Henry E. Jones, MC; CPT Jeffrey H. Reinhardt, MSC; Michael G. Rinaldi, MA

Arch Dermatol. 1973;108(1):61-65.

Abstract
Of 180 subjects, 35 (19%) fulfilled two of the following three criteria: clinical history, physical signs, positive culture. They were classified as chronically infected with dermatophytic fungi.

The technique and interpretation of skin testing with a purified trichophytin is discussed. Fifty-seven percent of the subjects manifested delayed sensitivity (DS) only, 14% immediate sensitivity (IS), and the remaining 29% were nonreactive.

In 93% of subjects manifesting only DS, there was an apparent clinical immunity to reinfection. Of the 35 subjects chronically infected, DS only was present in seven, no DS in 16 (nine manifested IS), and IS and DS coexisted in 12.

These data suggest that DS is a correlate of immunity, whereas lack of DS or coextistent IS is associated with susceptibility to chronic tinea infections.

Author Affiliations
USA; USA; SP/4, USA, San Francisco

From the Dermatology Research Division, Letterman Army Institute of Research, Presidio of San Francisco.

Footnotes
Accepted for publication March 13, 1973.

Read in part before the 14th International Congress of Dermatology, Padua/Venice, May 24, 1972; and read in part and shown in the Scientific Exhibit Section at the American Academy of Dermatology Meeting, Miami, Fla, Dec 3, 1972.

Reprint requests to Editor, Box 666, Letterman Army Institute of Research, Presidio of San Francisco 94129.

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