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Beate M. Czarnetzki, MD; Richard W. Belcher, MD

Arch Dermatol. 1974;109(1):36-39.

Abstract
The unstimulated nitroblue tetrazolium (NBT) test for infection was studied in 139 patients with various dermatoses and in 100 healthy controls. Leukocytes from controls showed a mean NBT response of 6.3% ± 5.5%. In comparison to controls, patients with cutaneous infections had elevated NBT values, but no statistically significant difference (P=> .05) was found in the mean NBT values of patients with bacterial (37.9% ± 27.5%) and viral (32.5 ± 25%) dermatoses. Elevated NBT tests were found in patients with allergic vasculitis, erythema multiforme, and several other noninfectious dermatoses. The unstimulated NBT test is of limited value as a diagnostic aid for detecting infection in patients with dermatologic disorders.

Author Affiliations
Margaret Fountain; Cleveland

From the Division of Dermatology, Cleveland Metropolitan General Hospital and Case-Western Reserve University School of Medicine, Cleveland.

Footnotes
Accepted for publication Aug 28, 1973.

Read before the Section on Dermatology at the 122nd annual convention of the American Medical Association, New York, June 23, 1973.

Reprint requests to Cleveland Metropolitan General Hospital, 3395 Scranton Rd, Cleveland 44109 (Dr. Belcher).

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ABSTRACT