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Michael R. Griffith, DDS; Kimie Fukuyama, MD; Denny Tuffanelli, MD; Sol Silverman, Jr., DDS

Arch Dermatol. 1974;109(2):195-199.

Abstract
A group of subjects with oral lesions representative of mucous membrane pemphigoid were studied by direct and indirect immunofluorescence. Biopsy specimens from seven of 11 subjects demonstrated deposition of one or more classes of immunoglobulin and complement in the region of the basement membrane. None of twelve sera showed circulating antibodies of the bullous pemphigoid or pemphigus types. The literature on immunological studies on patients with mucous membrane pemphigoid is reviewed, and a possible immunopathological relationship between bullous pemphigoid and mucous membrane pemphigoid is discussed.

Author Affiliations
San Francisco

From the Division of Oral Biology, School of Dentistry (Drs. Griffith and Silverman) and the Department of Dermatology, School of Medicine (Drs. Fukuyama and Tuffanelli), University of California, San Francisco.

Footnotes
Accepted for publication Sept 19, 1973.

Reprint requests to Department of Oral Biology, University of California, San Francisco, CA 94143 (Dr. Griffith).

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