This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John R. Luckasen, MD; Andrej Sabad; Robert W. Goltz, MD; John H. Kersey, MD

Arch Dermatol. 1974;110(3):375-377.

Abstract
Using E and EAC rossette assays, T and B lymphocytes were quantitated in patients with atopic eczema. Adult patients had percentages of T lymphocytes at the lower end of the range of normal. When evaluated as a group, their mean percentage was significantly lower than that of controls. B lymphocytes were present in normal percentages. Absolute numbers of both T and B lymphocytes were significantly decreased. These data suggest that there is a defect in cell-mediated immunity in the atopic population that may be important in the pathogenesis of the disease.

Author Affiliations
From the departments of dermatology (Drs. Luckasen and Goltz), laboratory medicine and pathology (Dr. Kersey and Mr. Sabad), University of Minnesota, Minneapolis.

Footnotes
Accepted for publication April 30, 1974.

Reprint requests to Box 98 Mayo Building, University of Minnesota, Minneapolis, MN 55455 (Dr. Luckasen).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Immune Dysregulation in Atopic Eczema
Bos et al.
Arch Dermatol 1992;128:1509-1512.
ABSTRACT  

Contact Sensitivity to Dinitrochlorobenzene Is Impaired in Atopic Subjects: Controversy Revisited
Rees et al.
Arch Dermatol 1990;126:1173-1175.
ABSTRACT  

Epidemic Herpes Simplex Virus Infection
CALLEN
Arch Pediatr Adolesc Med 1983;137:182-184.
ABSTRACT  

Localized Herpes Simplex Infections in Atopic Dermatitis
Leyden and Baker
Arch Dermatol 1979;115:311-312.
ABSTRACT  

Cell-Mediated Immunity In Vitro in Atopic Dermatitis
Horsmanheimo et al.
Arch Dermatol 1979;115:161-164.
ABSTRACT  

Delayed Cutaneous Hypersensitivity and Lymphocyte Transformation: Dissociation in Atopic Dermatitis
Elliott and Hanifin
Arch Dermatol 1979;115:36-39.
ABSTRACT  

Atopic Dermatitis, Impaired Cellular Immunity, and Molluscum Contagiosum
Pauly et al.
Arch Dermatol 1978;114:391-393.
ABSTRACT  

Staphylococcal Blepharitis
Smolin and Okumoto
Arch Ophthalmol 1977;95:812-816.
ABSTRACT  

Newer Concepts of Atopic Dermatitis
Hanifin and Lobitz
Arch Dermatol 1977;113:663-670.
ABSTRACT  

Thymus Lymphocytes of the Peripheral Blood in Patients With Alopecia Areata
Brown et al.
Arch Dermatol 1977;113:688-688.
ABSTRACT  

Immunodeficiencies in Severe Atopic Dermatitis: Depressed Chemotaxis and Lymphocyte Transformation
Rogge and Hanifin
Arch Dermatol 1976;112:1391-1396.
ABSTRACT  

T and B Lymphocytes in Contact and Atopic Dermatitis
Carapeto et al.
Arch Dermatol 1976;112:1095-1100.
ABSTRACT