You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 111 No. 11, November 1975 TABLE OF CONTENTS
  Archives
  •  Online Features
  SPECIAL ARTICLE
 This Article
 •References
 •Full text PDF
 •Correction
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Testosterone Metabolism in the Skin

A Review of Its Function in Androgenetic Alopecia, Acne Vulgaris, and Idiopathic Hirsutism Including Recent Studies With Antiandrogens

Vera H. Price, MD, FRCP(C)

Arch Dermatol. 1975;111(11):1496-1502.


Abstract

• Current concepts of testosterone metabolism in the human skin are reviewed, and the role of dihydrotestosterone in the pathophysiology of androgenetic alopecia, acne vulgaris, and idiopathic hirsutism is discussed. The hypothesis is submitted that a temporary, increased dihydrotestosterone formation at specific skin target sites at different ages causes the normal development of certain sexual characteristics, as well as the androgendependent skin disorders. Future treatment of these conditions is discussed in light of recent studies with antiandrogens.

(Arch Dermatol 111:1496-1502,1975)



Author Affiliations

From the Department of Dermatology, School of Medicine, University of California, San Francisco, and the Department of Dermatology, Kaiser-Permanente Medical Center, San Francisco.


Footnotes

Accepted for publication March 13, 1975.

Reprint requests to 2200 O'Farrell St, San Francisco, CA 94115 (Dr. Price).



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Treatment of Hair Loss
Price
NEJM 1999;341:964-973.
FULL TEXT  

MK-386, an Inhibitor of 5{alpha}-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen
Schwartz et al.
J. Clin. Endocrinol. Metab. 1997;82:1373-1377.
ABSTRACT | FULL TEXT  

Testosterone Increases Human Platelet Thromboxane A2 Receptor Density and Aggregation Responses
Ajayi et al.
Circulation 1995;91:2742-2747.
ABSTRACT | FULL TEXT  

Is Baldness Bad for the Heart?
Wilson and Kannel
JAMA 1993;269:1035-1036.
ABSTRACT  

Hirsutism
RITTMASTER and LORIAUX
ANN INTERN MED 1987;106:95-107.
ABSTRACT  

Lack of Efficacy of Polysorbate 60 in the Treatment of Male Pattern Baldness
Groveman et al.
Arch Intern Med 1985;145:1454-1458.
ABSTRACT  

Antiandrogenic Effects of Topically Applied Spironolactone on the Hamster Flank Organ
Weissmann et al.
Arch Dermatol 1985;121:57-62.
ABSTRACT  

Treatment of Hirsutism With Spironolactone
Cumming et al.
JAMA 1982;247:1295-1298.
ABSTRACT  

Juri Flap Procedure for the Treatment of Baldness: Two-Year Experience
Kabaker
Arch Otolaryngol Head Neck Surg 1979;105:509-514.
ABSTRACT  

Idiopathic Unilateral Facial Hirsutism: Report of a Case
Thomsen and Webster
Arch Dermatol 1979;115:99-100.
ABSTRACT  

Acne
Kaminester
JAMA 1978;239:2171-2172.
ABSTRACT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1975 American Medical Association. All Rights Reserved.