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David A. Paslin, MD; Edward A. Sprague, MD

Arch Dermatol. 1975;111(5):622-624.

Abstract
Indicators of the relative contribution of epidermis and dermis to the pathogenesis of psoriasis may be obtained from clinical observation. We studied a case of clinically characteristic and histologically identifiable plaque of chronic psoriasis occurring over transitional cell carcinoma metastatic to the dermis. The tumor substantially replaced the usual fibrous structure of the dermis, showing that a normally structured dermis is not requisite for the presence of psoriasis.

Author Affiliations
From the University of California School of Medicine, San Francisco, and the Kaiser Foundation Hospital, Redwood City, Calif. Dr. Sprague is now at Stanford University, Stanford, Calif.

Footnotes
Accepted for publication Oct 14, 1974.

Reprint requests to 1096 HSE, University of California Medical Center, San Francisco, CA 94143 (Dr. Paslin).

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