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Sea-Blue Histiocytes in Mycosis Fungoides
Bernard Robinowitz, MD;
Henry H. Roenigk, Jr., MD;
Marjorie M. Smith, MD
Arch Dermatol. 1975;111(9):1165-1167.
Abstract
A patient with tumor-stage mycosis fungoides and lymph node involvement had sea-blue (ceroid-containing) histiocytes in her bone marrow. Leukopenia, eosinophilia, and a mild type II β-hyperlipoproteinemia were also features. Seablue histiocytes were demonstrated in the skin after the mycosis fungoides infiltrate had cleared with treatment.
There is a possible interrelationship between the sea-blue histiocytes, the abnormal mycosis cells in the skin, and lipid metabolism.
Author Affiliations
From the departments of dermatology (Drs. Robinowitz and Roenigk) and pathology (Dr. Smith), the Cleveland Clinic Foundation, Cleveland.
Footnotes
Accepted for publication Nov 26, 1974.
Reprint requests to 9500 Euclid Ave, Cleveland, OH 44106 (Dr. Roenigk).
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