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Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy
Edward C. Gomez, MD, PhD;
Phillip Frost, MD
Arch Dermatol. 1976;112(11):1559-1562.
Abstract
A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with mildly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner.
(Arch Dermatol 112:1559-1562, 1976)
Author Affiliations
From the Departments of Dermatology and Pathology, Mount Sinai Medical Center, Miami Beach, Fla.
Footnotes
Accepted for publication Sept 17, 1975.
Reprint requests to Department of Pathology, Mount Sinai Medical Center, 4300 Alton Rd, Miami Beach, FL 33140 (Dr Gomez).
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