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  Vol. 112 No. 11, November 1976 TABLE OF CONTENTS
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Induction of Glycosuria and Hyperglycemia by Topical Corticosteroid Therapy

Edward C. Gomez, MD, PhD; Phillip Frost, MD

Arch Dermatol. 1976;112(11):1559-1562.


Abstract

• A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with mildly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner.

(Arch Dermatol 112:1559-1562, 1976)



Author Affiliations

From the Departments of Dermatology and Pathology, Mount Sinai Medical Center, Miami Beach, Fla.


Footnotes

Accepted for publication Sept 17, 1975.

Reprint requests to Department of Pathology, Mount Sinai Medical Center, 4300 Alton Rd, Miami Beach, FL 33140 (Dr Gomez).



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Systemic Absorption of Topical Steroids: Metabolic Effects as an Index of Mild Hypercortisolism
Garden and Freinkel
Arch Dermatol 1986;122:1007-1010.
ABSTRACT  

Dwarfism Following Long-term Topical Corticosteroid Therapy
Bode
JAMA 1980;244:813-814.
ABSTRACT  

Topical Halcinonide and Betamethasone Valerate Effects on Plasma Cortisol: Acute and Subacute Usage Studies
Gomez et al.
Arch Dermatol 1977;113:1196-1202.
ABSTRACT  





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