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Rudolf L. Baer, MD; Steven M. Leshaw, MD; Alan R. Shalita, MD

Arch Dermatol. 1976;112(4):479-481.

Abstract
• High daily doses of tetracycline (in most instances 2,000 mg) were administered over periods of 3 to 33 months to 31 patients suffering from unusually severe, disfiguring, and treatment-resistant forms of acne (papulopustular, cystic, and conglobated). The acne cleared in 14 patients, improved greatly in 13, improved only insignificantly in 3, and failed to improve in 1. Side-effects occurred in 15 of the 31 patients but necessitated cessation of treatment in only three.

(Arch Dermatol 112:479-481, 1976)

Author Affiliations
From the Department of Dermatology, New York University School of Medicine, New York.

Footnotes
Accepted for publication Aug 12, 1975.

Reprint requests to Department of Dermatology, New York University School of Medicine, 550 First Ave, New York, NY 10016 (Dr Baer).

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