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Sanders H. Berk, MD; Neal S. Penneys, MD, PhD; Gerald D. Weinstein, MD

Arch Dermatol. 1976;112(4):485-488.

Abstract
• In five patients with annular tinea corporis, the tritiated thymidine labeling indexes were determined in the rim, center, and intermediate areas of the lesion and compared with normal skin. Labeling indexes at the rim were much higher than those of normal skin (mean, 4.2 times). Labeling indexes elsewhere in the lesion were not significantly different from those of normal skin. Histologic examination showed epidermal thickening in all areas of the lesion as compared with normal skin. This study suggests that there is an increased epidermal turnover at the rim of annular dermatophytosis that may be important in the pathophysiology and morphogenesis of such lesions.

(Arch Dermatol 112:485-488, 1976)

Author Affiliations
From the Department of Dermatology, University of Miami, Miami, Fla. Dr Berk is currently with the Department of Dermatology, George Washington University, Washington, DC.

Footnotes
Accepted for publication Aug 12, 1975.

Reprint requests to Department of Dermatology, George Washington University, 2150 Pennsylvania Ave, Washington, DC 20037 (Dr Berk).

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