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Sebaceous Gland Inhibition From Combined Glucocorticoid-Estrogen Treatment
Peter E. Pochi, MD;
John S. Strauss, MD
Arch Dermatol. 1976;112(8):1108-1109.
Abstract
Sebum production in seven hirsute women was found to be markedly inhibited by low-dosage glucocorticoid therapy, usually 5 to 10 mg of prednisone daily, combined with the cyclic administration of ethinyl estradiol, either 80µg or 100µg daily, in the form of oral contraceptive medication. The average reduction of sebum secretion was 85.7%, from a pretreatment mean value of 3.07 mg of sebum to an average treatment level of 0.44 mg.
(Arch Dermatol 112:1108-1109, 1976)
Author Affiliations
From the Evans Memorial Department of Clinical Research, University Hospital, and the Department of Dermatology, Boston University School of Medicine, Boston.
Footnotes
Accepted for publication Oct 28, 1975.
Presented at the Society for Investigative Dermatology, Atlantic City, NJ, May 2, 1975.
Reprint requests to Department of Dermatology, Boston University School of Medicine, 80 E Concord St, Boston, MA 02118 (Dr Pochi).
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