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Early Clinical Appearance as Dermatitis Herpetiformis With Eosinopholic Spongiosis

Lt Col Frank B. Osteen, MC; Clayton E. Wheeler, Jr, MD; Robert A. Briggaman, MD; Elliot M. Puritz, MD

Arch Dermatol. 1976;112(8):1148-1152.

Abstract
• We encountered an unusual case of pemphigus foliaceus in which there were early clinical signs of dermatitis herpetiformis with eosinophilic spongiosis histologically. Numerous authors have appreciated that eosinophilic spongiosis occurs in early pemphigus foliaceus, usually in the preacantholytic stage when the lesions may clinically simulate dermatitis herpetiformis. Recognition of eosinophilic spongiosis may help differentiate early pemphigus from other vesiculobullous disorders.

(Arch Dermatol 112:1148-1152, 1976)

Author Affiliations
USAF

From the Department of Dermatology, University of North Carolina, Chapel Hill. Dr Osteen is now with the US Air Force Hospital, Langley Air Force Base, Va, and Dr Puritz is now in private practice in Smithtown, NY.

Footnotes
Accepted for publication June 19, 1975.

Reprint requests to Department of Dermatology, North Carolina Memorial Hospital, Chapel Hill, NC 27514 (Dr Wheeler).

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