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Immunofluorescent Studies

Beno Michel, MD; Samuel F. Bean, MD; Tadeus Chorzelski, MD; Charles F. Fedele, MD

Arch Dermatol. 1977;113(10):1403-1405.

Abstract
• Six patients with a vesiculobullous eruption of the type described by Brunsting and Perry as benign pemphigoid were studied by direct and indirect immunofluorescence. All six showed linear deposits of IgG but not IgM or IgA at the epidermal-dermal junction. One case also showed C3 deposition and one patient had circulating antibasement membrane zone antibodies in a titer of 1280. These data provide strong evidence that this condition belongs to the cicatricial pemphigoid-bullous pemphigoid spectrum of disease.

(Arch Dermatol 113:1403-1405, 1977)

Author Affiliations
From the Division of Dermatology, University Hospitals of Cleveland (Drs Michel and Fedele); Department of Dermatology, Baylor College of Medicine, Houston (Dr Bean); and the University of Warsaw, Poland (Dr Chorzelski).

Footnotes
Accepted for publication April 6, 1977.

Read in part before the 123rd American Medical Association annual meeting, Chicago, June 24, 1974.

Reprint requests to Division of Dermatology, University Hospitals of Cleveland, Cleveland, OH 44106 (Dr Michel).

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