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Scleroderma-like Changes in Chronic Graft vs Host Disease
Maj Richard L. Spielvogel, MC;
Robert W. Goltz, MD;
John H. Kersey, MD
Arch Dermatol. 1977;113(10):1424-1428.
Abstract
 A case of chronic graft vs host disease had scleroderma-like skin changes. Clinical progression was from poikiloderma to scleroderma, and histopathological changes and results of direct immunofluorescence were noted. It is probable that both cell-mediated (T-cell) and humoral (B-cell) mechanisms contribute to the pathogenesis of the graft vs host reaction.
(Arch Dermatol 113:1424-1428, 1977)
Author Affiliations
USAF
From the Departments of Dermatology (Drs Spielvogel and Goltz), Pediatrics (Dr Kersey), Laboratory Medicine (Dr Kersey), and Pathology (Dr Kersey), University of Minnesota, Minneapolis.
Footnotes
Accepted for publication Sept 10, 1976.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Air Force or the Department of Defense.
Reprint requests to Department of Dermatology, Box 98, University of Minnesota Hospitals, Minneapolis, MN 55455 (Dr Spielvogel).
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