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Lt Col Detlef K. Goette, MC; Lt Col Richard B. Odom, MC; Col Robert Owens, MC

Arch Dermatol. 1977;113(2):196-198.

Abstract
• An allergic contact dermatitis from fluorouracil developed in two patients 8 and 18 days respectively after institution of topical fluorouracil therapy. The character of the usual irritant dermatitis changed to that of an allergic dermatitis. Epicutaneous patch tests and intradermal tests with fluorouracil were reactive. Histologic specimens of positive test sites revealed the changes expected in allergic contact dermatitis. Twelve control subjects failed to react to intradermal fluorouracil tests.

(Arch Dermatol 113:196-198, 1977)

Author Affiliations
USA; USA; USA (Retired)

From the Dermatology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco.

Footnotes
Accepted for publication Jan 19, 1976.

The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.

Reprint requests to Technical Publications Editor, Letterman Army Medical Center, Presidio of California, CA 94129.

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