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  Vol. 113 No. 5, May 1977 TABLE OF CONTENTS
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Bullous Pemphigoid Responding to Sulfapyridine and the Sulfones

John R. Person, MD; Roy S. Rogers III, MD

Arch Dermatol. 1977;113(5):610-615.


Abstract

• Since 1968, a total of 84 patients with bullous pemphigoid have been seen at the Mayo Clinic. Of these, 41 were given a trial of sulfapyridine or dapsone, and six showed a significant response. In five patients, the condition was controlled completely. All responsive patients showed indirect and direct immunofluorescent tests indistinguishable from typical bullous pemphigoid. The patients, however, were somewhat younger (mean 54 years) than others having pemphigoid; and in two patients, biopsy specimens showed a reversal of the usual eosinophilic predominance over neutrophils. Three of the six patients were also diabetic.

(Arch Dermatol 113:610-615, 1977)



Author Affiliations

From the Mayo Clinic and Mayo Foundation, Rochester, Minn.


Footnotes

Accepted for publication July 21, 1976.

Reprint requests to Section of Publications, Mayo Clinic, 200 First St SW, Rochester, MN 55901 (Dr Person).



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