This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Clinical, Histopathologic, and Immunofluorescent Studies

Robert W. Romero, MD; Lee T. Nesbitt, Jr, MD; Richard J. Reed, MD

Arch Dermatol. 1977;113(6):741-748.

Abstract
• Eleven patients with a skin disorder in which clinical, histopathologic, and immunofluorescent findings showed overlap features of both lupus erythematosus (LE) and lichen planus (LP) were observed for several years.

Clinical lesions were extremely long-term and consisted primarily of livid red to violaceous atrophic patches and plaques, most common on acral aspects of the extremities. Nails were also commonly involved, often showing anonychia.

Histologic changes combined cell-rich and cell-poor lichenoid patterns in the papillary dermis, suggesting both LP and LE. The major immunofluorescent finding in all patients was the presence of ovoid bodies at the dermal-epidermal (D-E) junction and in the upper dermis. Most patients showed both a linear arrangement and a clustering pattern of these bodies. Four patients also had coexistant but poorly developed linear deposits of immunoglobulins and complement at the D-E junction.

(Arch Dermatol 113:741-748, 1977)

Author Affiliations
From the Department of Dermatology, Louisiana State University Medical Center (Drs Romero and Nesbitt), and the Department of Pathology, Tulane University School of Medicine (Dr Reed), New Orleans.

Footnotes
Accepted for publication Jan 6, 1977.

Reprint requests to Department of Dermatology, Louisiana State University Medical Center, 1542 Tulane Ave, New Orleans, LA 70112 (Dr Romero).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Annular Erythema as an Unusual Manifestation of Chronic Disseminated Lupus Erythematosus
Maciejewski
Arch Dermatol 1980;116:450-453.
ABSTRACT  

Lichen Planus and Discoid Lupus Erythematosus: Overlap Syndrome Associated With Cryoglobulinemia and Hypocomplementemia
Jamison et al.
Arch Dermatol 1978;114:1039-1042.
ABSTRACT