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William S. Lynch, MD; Henry H. Roenigk, Jr, MD

Arch Dermatol. 1977;113(9):1203-1208.

Abstract
• Mycophenolic acid is an antimetabolite used experimentally for the treatment of psoriasis. Thirty-eight patients were treated with mycophenolic acid. A doubleblind, placebo-controlled study demonstrated the efficacy of mycophenolic acid (P < .01). A long-term safety study showed the occurrence of hematologic abnormalities, viral infections, and carcinoma. The position of mycophenolic acid in the therapeutic treatment of psoriasis must await the results of a multicenter cooperative study.

(Arch Dermatol 113:1203-1208, 1977)

Author Affiliations
From the Cleveland Clinic Foundation.

Footnotes
Accepted for publication Nov 24, 1976.

Read in part before the Central State Dermatology Society meeting, Cleveland, May 18, 1975.

Reprint requests to Department of Dermatology, Northwestern University School of Medicine, 303 E Chicago Ave, Chicago, IL 60610 (Dr Roenigk).

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