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  Vol. 114 No. 10, October 1978 TABLE OF CONTENTS
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The Genetics of Follicular Atrophoderma

Helen Ollendorff Curth, MD

Arch Dermatol. 1978;114(10):1479-1483.


Abstract

• Follicular atrophoderma apparently does not occur alone but is associated with other abnormalities. It is present in three groups: (1) If it is associated with chondrodystrophia calcificans congenita, it occurs only in girls and is due either to an X-chromosomal gene causing the changes in the heterozygote (ie, in the female sex) and prenatal death in the hemizygous state (ie, in the male sex), or to an autosomal dominant gene with expression almost wholly limited to the female sex; (2) If it is associated with Bazex's syndrome, it occurs in male and female persons in successive generations and is due either to an autosomal dominant gene or to an X-linked dominant gene; and (3) If it occurs in association with keratosis palmoplantaris dissipata, keratosis follicularis, and hyperhidrosis palmoplantaris, it may be due to a recessive gene or a mutation.

(Arch Dermatol 114:1479-1483, 1978)



Author Affiliations

From the Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York.


Footnotes

Accepted for publication April 5, 1978.

Read before the Meeting of the Society for Dermatological Genetics, Dallas, Dec 7, 1977.

Reprint requests to 650 W 261st St, New York, NY 10471 (Dr Curth).



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