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Takeshi Horio, MD; Takashi Murai, MD; Kouichi Ikai, MD

Arch Dermatol. 1978;114(10):1498-1500.

Abstract
• A photosensitive lichen planus-like eruption developed in a 63-year-old man during postoperative chemotherapy with 1-(2-tetrahydrofuryl)-5-fluorouracil. The action spectrum for the photosensitivity was in the long-wave ultraviolet light (UV-A). The reaction was reproducible on readministration of the drug and exposure to UV-A. At the time of this test, a flare-up phenomenon was observed at previously involved sites. The photopatch test was negative with the drug. Patients taking the drug who had no dermatitis were not sensitive to UV-A. These observations suggest that the photosensitivity that occurred in the patient was possibly photoallergic.

(Arch Dermatol 114:1498-1500, 1978)

Author Affiliations
From the Department of Dermatology, Faculty of Medicine, Kyoto University, Kyoto, Japan.

Footnotes
Accepted for publication Nov 18, 1977.

Reprint requests to Department of Dermatology, Faculty of Medicine, Kyoto University, Kyoto, 606 Japan (Dr Horio).

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