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Multiple Hamartoma Syndrome (Cowden's Disease)
Col Donald D. Nuss, MC;
Col John L. Aeling, MC;
Maj Donald E. Clemons, MC;
Maj Wallace N. Weber, MC
Arch Dermatol. 1978;114(5):743-746.
Abstract
The four male patients with multiple hamartoma syndrome (Cowden's disease) in this report, have most of the previously reported findings associated with this syndrome and several important unreported findings that include multiple cutaneous trichilemmomas, cafe-au-lait spots, cutaneous squamous cell carcinoma, pathologic fracture, craniomegaly, probable malignant lung tumor, retinal glioma, drusens of the optic disk and retina, pseudotumor cerebri, mediastinal mass, and multiple small papillomatous lesions of the esophagus, stomach, and duodenum.
(Arch Dermatol 114:743-746, 1978)
Author Affiliations
USA; USA; USA; USA
From the Dermatology Service, Fitzsimons Army Medical Center, Denver. Dr Clemons is now with Second General Hospital, New York, and Dr Weber is now with Munson Army Hospital, Fort Leavenworth, Kan. Dr Nuss is in private practice.
Footnotes
Accepted for publication Dec 21, 1977.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Army or the Department of Defense.
Reprint requests to Dermatology Service, Fitzsimons Army Medical Center, Denver, CO 80240 (Dr Aeling).
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