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Lucio's Phenomenon and Diffuse Nonnodular Lepromatous Leprosy
Thomas H. Rea, MD;
Norman E. Levan, MD
Arch Dermatol. 1978;114(7):1023-1028.
Abstract
• The records of ten patients with Lucio's phenomenon showed clinical and histopathological changes similar to those described by others. Lucio's phenomenon is a syndrome distinct from erythema nodosum leprosum as indicated by an absence of fever, leukocytosis and tenderness, a failure to respond to thalidomide, and a restriction to patients with diffuse nonnodular lepromatous leprosy. Lymphopenia associated with splenomegaly in three patients and glomerulonephritis in one patient were unexpected findings of unknown relevance.
(Arch Dermatol 114:1023-1028, 1978)
Author Affiliations
From the Section of Dermatology, Department of Medicine, University of Southern California, School of Medicine, and the Department of Dermatology, Los Angeles County-University of Southern California Medical Center, Los Angeles.
Footnotes
Accepted for publication March 8, 1978.
Reprint requests to Section of Dermatology, Department of Medicine, University of Southern California, School of Medicine, 2025 Zonal Ave, Los Angeles, CA 90033 (Dr Rea).
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