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Congenital Poikiloderma With Features of Hereditary Acrokeratotic Poikiloderma
Martin B. Draznin, MD;
Nancy B. Esterly, MD;
David F. Fretzin, MD
Arch Dermatol. 1978;114(8):1207-1210.
Abstract
• An adolescent boy with a bizarre progressive poikiloderma had episodic acral blistering and the development of palmar and plantar keratosis suggestive of hereditary acrokeratotic poikiloderma. Growth and development had been normal. Vesicobullous lesions were said to be present at birth and during early infancy. No family members were similarly affected. Results of laboratory studies were normal. Histological sections of skin demonstrated epidermal atrophy in some areas, increased epidermal melanin fibrosis of the papillary dermis, and modest capillary proliferation.
(Arch Dermatol 114:1207-1210, 1978)
Author Affiliations
From the Divisions of Dermatology, Department of Pediatrics (Drs Draznin and Esterly) and Department of Medicine (Dr Fretzin), and the Department of Pathology (Dr Fretzin), Michael Reese Hospital and Medical Center, Chicago. Dr Draznin is now with the University of Virginia School of Medicine, Charlottesville, and Dr Esterly is with Northwestern University Medical School, Chicago.
Footnotes
Accepted for publication Jan 30, 1978.
Reprint requests to Department of Pediatrics, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614 (Dr Esterly).
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