This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Study of 21 Patients

Virginia I. Sulica, MD; Philip H. Cooper, MD; F. Michael Pope, MD; George W. Hambrick, Jr, MD; Ben M. Gerson, MD; Victor A. McKusick, MD

Arch Dermatol. 1979;115(1):40-42.

Abstract
Skin biopsy specimens from 21 patients with Ehlers-Danlos syndrome (EDS) were compared with controls. With two exceptions, the appearance of the dermal collagen and elastic tissue as seen in the two groups was indistinguishable. One example of type 4 EDS contained a dermis composed of fibers that resembled actinically damaged elastic tissue. The single example of type 6 EDS contained particularly thin collagen fibers. The dermal thickness of specimens of EDS was similar to that of controls, although the abnormal-appearing specimen of type 4 EDS was also abnormally thin. Since the other two biopsy specimens of type 4 appeared to be within the range of normal, there may be heterogeneity in this form of EDS.

(Arch Dermatol 115:40-42, 1979)

Author Affiliations
From the Department of Dermatology (Drs Sulica and Hambrick), the Division of Medical Genetics (Drs Pope and McKusick), and the Department of Pathology (Dr Gerson), Johns Hopkins Hospital, Baltimore; and the Departments of Pathology and Dermatology (Dr Cooper), University of Virginia, Charlottesville. Dr Sulica is now with the Division of Dermatology, Georgetown University, Washington, DC.

Footnotes
Accepted for publication Aug 16, 1978.

Reprints not available.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

The Invisible Dermatoses
Kligman
Arch Dermatol 1991;127:1375-1382.
ABSTRACT