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Performance of Six Sunscreen Formulations on Human SkinA Comparison
Robert M. Sayre, PhD;
Edward Marlowe, PhD;
Patricia Poh Agin, MS;
Gordon J. LeVee, PhD;
E. William Rosenberg, MD
Arch Dermatol. 1979;115(1):46-49.
Abstract
Indoor and outdoor tests were performed on human volunteers to determine the protection offered by six commercially available products containing single sunscreen ingredients and combinations of ingredients. Indoor solar simulator studies were performed to determine the inherent efficacy of each product, including use of a whirlpool treatment to evaluate the resistance of each product to wash off. The outdoor study included a tenminute swimming period followed by sunlight exposure. In all tests, the combination of 7% octyl-dimethyl p-aminobenzoic acid ester and 3% oxybenzone was substantially more effective in protecting against sunburn than any other formula tested, including 5% p-aminobenzoic acid (PABA).
(Arch Dermatol 115:46-49, 1979)
Author Affiliations
From the Department of Photobiology Research, Schering-Plough, Inc (Drs Sayre, Marlowe, and LeVee, and Ms Agin), and the University of Tennessee Center for the Health Sciences, College of Medicine (Drs Rosenberg and Sayre) and Pharmacy (Dr Marlowe), Memphis.
Footnotes
Accepted for publication July 26, 1978.
Reprint requests to Department of Photobiology Research, Schering-Plough, Inc, 3030 Jackson Ave, Memphis, TN 38151 (Dr Sayre).
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