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Ira Greene, MD; Alvin J. Cox, MD

Arch Dermatol. 1979;115(10):1200-1202.

Abstract
Histologic examination of skin from 52 patients under continued treatment with methoxsalen and long-wave ultraviolet irradiation (PUVA) disclosed small superficial dermal deposits in six subjects who had completed one year of therapy and in six subjects who had completed two years of therapy. These deposits, by light and electron microscopic criteria, are similar to those of lichen amyloidosus. Amyloid deposition should be regarded as a possible complication of PUVA therapy.

(Arch Dermatol 115:1200-1202, 1979)

Author Affiliations
From the Department of Dermatology, Stanford (Calif) University School of Medicine.

Footnotes
Accepted for publication March 29, 1979.

Reprint requests to the Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305 (Dr Cox).

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