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Skin Cancer and Arsenical Intoxication From Well Water
Sheldon L. Wagner, MD;
Jerome S. Maliner, MD;
William E. Morton, MD, DPH;
Robert S. Braman, PhD
Arch Dermatol. 1979;115(10):1205-1207.
Abstract
A case of acute arsenical intoxication arising from ingested well water containing only 1.2 ppm of arsenic is reported. After a latent period of 14 years, multiple cutaneous basal cell carcinomas developed. The water was analyzed for a variety of other trace elements and compounds and no evidence for the existence of other carcinogens was found. This study strengthens the concept that arsenic is a carcinogen. The role of a possible selenium deficiency is also discussed.
(Arch Dermatol 115:1205-1207, 1979)
Author Affiliations
From the Environmental Health Sciences Center, Oregon State University, Corvallis, Ore (Dr Wagner); the Environmental Medicine Division, University of Oregon Health Sciences Center, Portland (Dr Morton); and the Department of Chemistry, University of South Florida, Tampa (Dr Braman). Dr Maliner is in private practice in Eugene, Ore.
Footnotes
Accepted for publication May 25, 1979.
Reprint requests to the Environmental Health Sciences Center, Oregon State University, Corvallis, OR 97331 (Dr Wagner).
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