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A Cutaneous Marker for a Distinct Lupus Erythematosus Subset

Richard D. Sontheimer, MD; Jesse R. Thomas; James N. Gilliam, MD

Arch Dermatol. 1979;115(12):1409-1415.

Abstract
We have characterized the clinical and laboratory features of 27 patients who had in common a recurring, superficial, nonscarring type of cutaneous lupus erythematosus (LE) that occurred in a characteristic distribution (subacute cutaneous lupus erythematosus [SCLE]). This clinically distinct form of cutaneous LE has not previously been analyzed as a separate entity and thus, its clinical importance has not been fully appreciated. We found that these patients frequently had a mild systemic illness marked by musculoskeletal complaints and serologic abnormalities. Forty-eight percent had systemic LE by American Rheumatism Association criteria; however, none had serious CNS or renal disease. Thus, those with SCLE are a subset of patients with LE who generally have an illness intermediate in severity between discoid LE and severe systemic LE.

(Arch Dermatol 115:1409-1415, 1979)

Author Affiliations
From the Dermatology Division, Department of Internal Medicine, University of Texas Health Science Center at Dallas (Drs Sontheimer and Gilliam); and the University of Texas Southwestern Medical School (Mr Thomas), Dallas.

Footnotes
Accepted for publication July 6, 1979.

Read in part at the annual meetings of the American Academy of Dermatology, San Francisco, Dec 5,1978, and the American Rheumatism Association, Denver, June 1, 1979.

Reprint requests to the Dermatology Division, 5323 Harry Hines Blvd, Dallas, TX 75235 (Dr Sontheimer).

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