This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

John W. Petrozzi, MD; John O. Barton; Albert Kligman, MD

Arch Dermatol. 1979;115(4):436-439.

Abstract
Analysis of standard fluorescent sunlamps (Westinghouse) indicates that in addition to UVB (290 to 320 nm), a considerable amount of UVA (320 to 400 nm) is also present in their emissions. Since the benefits of topical psoralen administration and UVA have already been demonstrated, and prior experience by ourselves and others with UVB has indicated that some psoriasis benefited from UVB alone, localized areas and plaques of 20 patients were treated with topical administration of psoralens and fluorescent sunlamp bulbs to determine if such a light source with this emission spectrum would be advantageous. Results indicated a total resolution in 17 of 20 patients after an average of 18 treatments. Adverse blistering phototoxic reactions and excessive hyperpigmentation were not encountered. The UVB erythema response of normal skin served as the guide to light dosage in the same manner as administration of the Goeckerman regimen. Therefore, the use of psoralens was very effective when combined with fluorescent sunlamp irradiation; however, the potential risks of photocarcinogenicity makes this treatment experimental and should be reserved for recalcitrant cases.

(Arch Dermatol 115:436-439, 1979)

Author Affiliations
Octavio de los Reyes

From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, and the Philadelphia Veterans Administration Hospital.

Footnotes
Accepted for publication Oct 27, 1978.

Reprint requests to Department of Dermatology (111-P), Philadelphia Veterans Administration Hospital, University and Woodland Avenues, Philadelphia, PA 19104 (Dr Petrozzi).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Treatment of Palmoplantar Psoriasis With Topical Methoxsalen Plus Long-Wave Ultraviolet Light
Abel et al.
Arch Dermatol 1980;116:1257-1261.
ABSTRACT  

Comparison of Crude Coal Tar and Topical Methoxsalen in Treatment of Psoriasis
Petrozzi and Barton
Arch Dermatol 1979;115:1061-1063.
ABSTRACT