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A Breakdown in Immune Regulation

Luis A. Diaz, MD; Roman W. Glamb, MD; Joseph Silva, Jr, MD

Arch Dermatol. 1980;116(1):77-79.

Abstract
• The clinical findings of pemphigus vulgaris, rheumatoid arthritis, and Sjögren's syndrome were found in a patient displaying immunological abnormalities found in pemphigus vulgaris, systemic lupus erythematosus, rheumatoid arthritis, and Hashimoto's thyroiditis. Some of the antigen-antibody systems detected in this case were further identified. Our patient may be an example of severe failure in immune regulation.

(Arch Dermatol 116:77-79, 1980)

Author Affiliations
From the Departments of Dermatology (Drs Diaz and Glamb) and Internal Medicine (Dr Silva), University of Michigan Medical School, Ann Arbor.

Footnotes
Accepted for publication Sept 19, 1979.

Reprint requests to Department of Dermatology, University of Michigan Medical School, 1405 E Ann St, Ann Arbor, MI 48109 (Dr Diaz).

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