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Nicole Hunziker, MD; Robert Brun, PhD

Arch Dermatol. 1980;116(11):1266-1268.

Abstract
• Five patients with atopy who had chronic dermatophytosis manifested an immediate and strong trichophytin skin reaction but no delayed reaction. This phenomenon may be caused by the neutralization of injected antigen by serum antibodies during the immediate reaction. When we injected a second dose of trichophytin into the wheal of the immediate reaction, 20 minutes after the first injection, a strong delayed reaction was elicited, demonstrating cell-mediated immune responses in these patients.

(Arch Dermatol 116:1266-1268, 1980)

Author Affiliations
From the Department of Dermatology, University of Geneva.

Footnotes
Accepted for publication March 13, 1980.

Read before the 60th Congress of the Swiss Society of Dermatology, Bern, Switzerland, Oct 14, 1978.

Reprint requests to Department of Dermatology, University of Geneva, 1211 Geneva 4, Switzerland (Dr Hunziker).

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