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Lymphocyte Cyclic Nucleotide and Prostaglandin Content in Psoriasis: A Preliminary Report
Shmuel Harpaz, PhD;
Aharon Fink, MD;
Fela Zuckerman, MD;
Essawy Muhammad, MSc
Arch Dermatol. 1980;116(4):427-428.
Abstract
Lymphocytes from psoriatic patients were found to contain reduced levels of adenosine 3':5'-cyclic phosphate, guanosine 5'-cyclic phosphoric acid, and prostaglandin E, as compared with lymphocytes from normal subjects. The difference in prostaglandin F levels between psoriatic and control subjects was not statistically significant. These results could point to an immunologic defect in the immune system in psoriasis.
(Arch Dermatol 116:427-428, 1980)
Author Affiliations
From the Endocrinology Laboratory (Dr Harpaz and Mr Muhammad) and the Departments of Internal Medicine (Dr Fink) and Dermatology (Dr Zuckerman), Central Emek Hospital, Afula, Israel.
Footnotes
Accepted for publication Sept 11, 1979.
Reprint requests to Endocrinology Laboratory, Central Emek Hospital, Afula, Israel (Dr Harpaz).
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