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Cutaneous Macroglobulinosis
C. William Hanke, MD;
Willard D. Steck, MD;
Wilma F. Bergfeld, MD;
Rafael Valenzuela, MD;
James K. Weick, MD;
Jess R. Young, MD;
Earl G. Gross, MD
Arch Dermatol. 1980;116(5):575-577.
Abstract
• A patient with Waldenström's macroglobulinemia had firm, translucent papules and nodules on the extremities. Clinically, the skin lesions were suggestive of amyloidosis cutis. Histologically, a homogeneous eosinophilic material was observed in the upper dermis and encasing the hair follicles. Special histochemical stains, electron microscopy, and immunofluorescence microscopy identified the material as IgM.
(Arch Dermatol 116:575-577, 1980)
Author Affiliations
From the Departments of Dermatology (Drs Hanke, Steck, Bergfeld, and Gross), Immunopathology (Dr Valenzuela), Hematology-Oncology (Dr Weick), and Peripheral Vascular Disease (Dr Young), The Cleveland Clinic Foundation. Dr Hanke is now with Indiana University School of Medicine, Indianapolis.
Footnotes
Accepted for publication Dec 18, 1979.
Reprint requests to Department of Dermatology, Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44106 (Dr Steck).
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