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Jeffrey L. Marx, MD; Richard K. Scher, MD

Arch Dermatol. 1980;116(9):1023-1024.

Abstract
• Ten patients with generalized psoriasis, which included nail involvement, were treated with total-body oral photochemotherapy. A combination of methoxsalen and high-intensity ultraviolet A radiation was employed and its therapeutic efficacy in nail psoriasis ascertained. Among the ten patients, there were 26 instances of the following nail signs: pitting, onycholysis, "oil drop" change, subungual hyperkeratosis, nail-plate crumbling, proximal nail-fold psoriasis, and onychorrhexis. Of the 26, eighteen improved by 50% or more. Only pitting failed to respond to therapy in all of the eight patients who had this change.

(Arch Dermatol 116:1023-1024, 1980)

Author Affiliations
From the Department of Dermatology, New York University Medical Center.

Footnotes
Accepted for publication Dec 12, 1979.

Reprint requests to 193 Broadway, Amityville, NY 11701 (Dr Scher).

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