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Familial Variant of Dermatofibroma With Malignancy in the Proband
John T. Roberts, MB ChB, FRCS(C);
Ernest H. Byrne, MD;
Donald Rosenthal, MD, FRCP(C)
Arch Dermatol. 1981;117(1):12-15.
Abstract
Multiple fibrous histiocytomas of the dermis (dermatofibromas) were found in six males of one family. A number of the tumors fell within the histologic patterns commonly encountered in dermatofibromas, but some were unusually large and others were cytologically atypical. In addition, the proband died of a malignant fibrous histiocytoma of the lung. We believe that this is a syndrome and a familial variant of a common dermal entity.
(Arch Dermatol 117:12-15, 1981)
Author Affiliations
From the Departments of Pathology (Dr Roberts) and Medicine (Drs Byrne and Rosenthal), McMaster University and Henderson General Hospital, Hamilton, Ontario.
Footnotes
Accepted for publication March 13, 1980.
Presented in part at the meeting of the Canadian Association of Pathologists, Hamilton, Ontario, June 29, 1977.
Reprint requests to Department of Laboratory Medicine, Henderson General Hospital, 711 Concession St, Hamilton, Ontario, Canada L8V 1C3 (Dr Roberts).
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