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Bullous Amyloidosis
Per Westermark, MD;
Sven Öhman, MD;
Margareta Domar, MD;
Knut Sletten, PhD
Arch Dermatol. 1981;117(12):782-784.
Abstract
• The distribution pattern of amyloid deposition varies greatly in systemic amyloidosis. In primary and myeloma-associated amyloidosis, skin manifestations are common. Three patients with myeloma-associated amyloidosis had bullae or signs of increased skin fragility caused by cleavage in extensive dermal amyloid deposits. The bullae in bullous amyloidosis are, therefore, unique since they are intradermal, not subepidermal.
(Arch Dermatol 1981;117:782-784)
Author Affiliations
From the Departments of Pathology (Dr Westermark) and Dermatology (Drs Öhman and Domar), University Hospital, Uppsala, Sweden; and the Institute of Biochemistry, University of Oslo, Norway (Dr Sletten).
Footnotes
Accepted for publication March 19, 1981.
Reprint requests to Department of Pathology, University Hospital, Box 553, Uppsala S-751 22, Sweden (Dr Westermark).
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